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Menchaca first became interested in performing as a student at Central High School. After graduating, he attended Texas A&M University, earning a bachelor's degree in English; it was also where he acted in his first play. He participated in a summer acting program at the Circle in the Square Theatre School in Manhattan before pursuing an acting career in his twenties. He is an alumnus of the William Esper Studio.

Menchaca was co-director, co-writer and lead actor of the 2013 Heartland Film Festival movie This Is Where We Live.

In 2015, he played a lead role as Bob Stevens, a veteran struggling with memory loss, in the Kyle Ham-directed film Reparation. It earned him the best actor award at the BreckenridgeFilm Festival, with the film receiving a further 10 festival awards, including the Austin Film FesFestival'sdience Choice prize and Best Film at the Santa Fe Film Festival.

In the 2018 Netflix television series Ozark, Menchaca had a recurring role as Russ Langmore, a man struggling to suppress his homosexuality. He has had regular roles on television in The Sinner and Manifest. He appeared again on TV with Jason Bateman in 2019 in the Stephen King horror miniseries The Outsider, portraying Jack Hoskins for all 10 episodes.

In 2020, Menchaca won Best Actor in a Feature at the Mammoth Film Festival Awards for his performance as Sam in the John Hyams thriller Alone alongside co-star Jules Willcox. He performed his stunts in the film, including a fight scene in the mud with Willcox. He received a further award for Best Actor in 2020 at the Oxford International Film Festival (OXIFF) in the UK for his portrayal of 'Th' Man' i' #Like, directed by Sarah Pirozek. In 2021, he starred in the Santiago Menghini-directed Netflix horror movie No One Gets Out Alive with co-star Cristina Rodlo.

On October 6, 2022, Menchaca married British actress Lena Headey in Apulia, Italy. He is of Mexican descent on his paternal side.